What is Cialis?

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Cialis, or tadalafil, is a PDE5 inhibitor drug most commonly used to treat erectile dysfunction. It may also be used to treat BPH or benign enlargement of the prostate and pulmonary arterial hypertension. The medication is marketed under the name Adcirca and given in higher doses to treat pulmonary hypertension. PDE5 inhibitors block the enzyme PDE5 which exists in some smooth muscle tissues in the body. These medications stop the PDE5 enzyme from degrading cGMP, a nucleotide that acts to relax smooth muscle tissues. Relaxed smooth muscle tissue enhances the propensity for erectile function. Cialis differs from other PDE5 inhibitors like Viagra and Levitra in that it has a longer half-life of up to 17.5 hours and may function in the body for up to 36 hours.

 

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